Email: [email protected] Bulk botanical extract manufacturing since 2014
Supercritical CO2 Botanical Extract Production Facility - RAAG Biotech Co., Ltd.
Technical Manufacturing Authority

High-Purity Supercritical CO2 Fluid Extraction (SFE-CO2)

RAAG Biotech Co., Ltd. is a premier GMP-audited manufacturer and global bulk supplier specializing in Supercritical CO2 Fluid Extraction (SFE-CO2) technology. By utilizing pressurized carbon dioxide in its supercritical state above 31.1°C and 73.8 bar, our automated production lines extract active lipophilic compounds, volatile essential oils, and functional oleoresins without exposing delicate botanical markers to high thermal degradation or organic solvent contaminants.

Our extraction facilities operate under strict ISO22000, FSSC22000, HALAL, and KOSHER quality management systems. Every batch of CO2 extract is verified by in-house HPLC and GC-MS testing, guaranteeing zero chemical solvent residues (100% Hexane-Free, Ethanol-Free), low heavy metals, and verified active concentration for nutraceutical, pharmaceutical, cosmetic, and food applications worldwide.

Solvent-Free Guarantee

100% natural supercritical CO2 process leaving zero organic solvent residues in final products.

Thermal Marker Protection

Low extraction temperature (31–50°C) prevents oxidative and heat degradation of actives.

Audit-Ready Files

Complete lot-level COA, GC-MS fingerprint, MSDS, Allergen & Pesticide screening reports.

Customized Scale-Up

Pilot sample batches (1 kg) to multi-ton commercial bulk supply within short lead times.

Supercritical CO2 Extraction Equipment at RAAG Biotech Co., Ltd.
Technical Advantages

Why B2B Buyers Choose Supercritical CO2 Extracts

Supercritical fluid extraction represents the gold standard in green chemistry, offering unprecedented purity and stability for high-end nutritional and dermatological formulations.

01

Thermolabile Protection

Operating under gentle temperatures (31–50°C) preserves sensitive essential fatty acids (Omega-3/6/7/9), delicate aromatic terpenes, and thermolabile carotenoids.

02

Pure & Residue-Free

Carbon dioxide converts back to harmless gas upon depressurization, resulting in clean-label botanical ingredients devoid of hexane, acetone, or heavy chemical residues.

03

Controlled Selectivity

Precision tuning of pressure and temperature parameters allows targeted extraction of desirable phytochemicals while excluding unwanted waxes or ballast compounds.

04

Eco-Friendly Closed Loop

Our extraction setup recycles and reuses non-toxic natural CO2 in a fully closed loop, minimizing environmental footprint and energy consumption.

Bulk Product Portfolio

Featured CO2 Supercritical Extracts & Botanical Oils

Standardized, audit-ready botanical extracts and functional lipid complexes manufactured for global B2B procurement.

Gromwell Root CO2 Extract Oleoresin
Shikonin ≥30% Oleoresin

Gromwell Root CO2 Extract

Rich in Shikonin and Alkannin derivatives. Solvent-free supercritical oleoresin designed for cosmetic soothing formulations and therapeutic skin care.

Cinnamon Bark Essential Oil Bulk
Cinnamaldehyde ≥75%

Cinnamon Bark Oil

Pure steam-distilled and CO2 fractionated essential oil delivering high natural cinnamaldehyde content for flavor, fragrance, and microbial control applications.

Peony Seed Oil Omega-3 Rich
Alpha-Linolenic Acid ≥40%

Peony Seed Oil

Supercritical CO2 extracted botanical seed oil abundant in essential Omega-3 fatty acids, ideal for high-end nutritional softgels and anti-aging cosmetics.

Borage Seed Oil GLA Complex
Gamma-Linolenic Acid ≥20%

Borage Seed Oil

Cold-processed and CO2 refined plant oil supplying concentrated GLA for cellular health, anti-inflammatory dietary supplements, and skin barrier repair.

Sandalwood Essential Oil CO2 Extract
Total Santalol ≥85%

Sandalwood Oil

High-purity aromatic CO2 extract retaining authentic Santalol profiles for premium aromatherapy, luxury perfumery, and functional skincare actives.

Pomegranate Seed Oil Punicic Acid
Punicic Acid ≥70%

Pomegranate Seed Oil

Supercritical CO2 extract containing rare conjugated linolenic acid (Punicic Acid) for powerful cellular antioxidant protection and dermatological products.

Sacha Inchi Seed Oil Omega 3 6 9
Total Omegas ≥90%

Sacha Inchi Seed Oil

Nutrient-dense botanical oil offering a balanced spectrum of Omega-3, 6, and 9 fatty acids for cardiovascular and skin nutrition supplement formulations.

Sea Buckthorn Berry Oil CO2 Extract
Palmitoleic Acid (Omega-7) ≥30%

Sea Buckthorn Berry Oil

Pure fruit pulp CO2 extract rich in Omega-7, natural beta-carotene, and vitamin E derivatives for mucosal health and premium skin rejuvenation.

Gromwell Root Powder Botanical Material
Milled Root Fine Powder

Gromwell Root Powder

Low-temperature ground raw botanical powder with strictly verified heavy metal and microbiological compliance for herbal compounding.

Customization Capabilities

Tailored OEM Solutions & Compounding Formulations

We work directly with R&D scientists and purchasing managers to deliver custom active concentrations, carriers, and water-dispersible forms.

Nutraceutical Formulations

  • Softgel Ready Oils: Pre-diluted or concentrated oil matrices standardized with organic MCT or sunflower oil carriers.
  • Water-Dispersible Powders: Spray-dried micro-encapsulated CO2 extracts on gum arabic or acacia fiber for direct beverage powders.
  • Bioavailability Enhancers: Synergistic oil blends combining botanical actives with natural piperine or lecithin complexes.

Cosmetic & Skincare Actives

  • Cold-Process Integration: Lipophilic oleoresins engineered for smooth emulsification into creams, lotions, and serums.
  • Preservative-Free Actives: Pure botanical oil extracts stabilized with natural non-GMO mixed tocopherols (Vitamin E).
  • Liposomal Encapsulation: Custom micro-emulsions optimized for deep dermal penetration and targeted skin barrier delivery.

Clean-Label Food & Flavor

  • Solvent-Free Flavoring: Highly concentrated spice oleoresins (cinnamon, ginger, black pepper) for clean-label food systems.
  • Natural Color Solutions: Carotenoid-rich CO2 plant extracts providing stable oil-soluble color profiles.
  • Natural Antioxidant Systems: Supercritical rosemary oleoresin standardized in carnosic acid for lipid shelf-life extension.
Target Industries

Applications Across High-Standard Sectors

Our supercritical CO2 extracts meet rigorous international pharmacopeial and regulatory standards across diverse commercial industries.

Nutraceutical dietary supplements applications
Nutraceuticals & Dietary Supplements
Cosmetics and skin care formulations
Cosmetics & Personal Care
Functional foods and beverage industry
Functional Foods & Beverages
Phytopharmaceutical botanical drugs
Phytopharmaceuticals & Herbal Remedies
Aromatherapy and essential oils
Aromatherapy & Fine Fragrance
Animal health and botanical nutrition
Animal Nutrition & Veterinary Health
Quality Assurance

Supercritical CO2 Manufacturing Workflow

From raw botanical intake to nitrogen-purged drum sealing, every step is governed by standard operating procedures under ISO & GMP controls.

01

Herb Intake & Testing

Raw herbs sourced from contracted planting bases undergo identity, moisture, pesticide, and heavy metal screening.

02

Supercritical Extraction

Controlled CO2 pressure (73.8–300 bar) and low temperature (31–50°C) selectively extract targeted active lipophilic compounds.

03

Phase Separation

Depressurization causes CO2 gas to evaporate completely, yielding pure, solvent-free botanical oil and oleoresin.

04

HPLC & GC-MS Testing

In-house quality chemists verify active marker assay percentage, fatty acid profile, micro counts, and zero residual solvents.

05

Sealed Packaging

Finished lots are packaged under nitrogen gas protection in food-grade aluminum or stainless drums accompanied by batch COA.

Technical FAQ

Frequently Asked Questions by Overseas Procurement Teams

Direct technical responses from RAAG Biotech Co., Ltd. quality assurance and international export specialists.

Supercritical CO2 extraction utilizes carbon dioxide in a state above its critical temperature (31.1°C) and critical pressure (73.8 bar). In this phase, CO2 exhibits the dissolving power of a liquid combined with the high penetration rate of a gas, enabling efficient extraction of lipophilic phytochemicals, essential oils, and bioactive fatty acids without organic chemical solvents.

Unlike traditional solvent extraction using hexane, ethanol, or acetone, supercritical CO2 extraction operates at lower temperatures (protecting heat-sensitive markers) and leaves absolutely zero chemical solvent residue. The natural CO2 gas evaporates completely upon depressurization, making it the preferred choice for premium, clean-label, and organic-compliant market positioning.

Every bulk lot shipped by RAAG Biotech Co., Ltd. comes complete with a batch-specific Certificate of Analysis (COA with HPLC or GC-MS assay), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), Allergen Statement, Non-GMO Declaration, Process Flow Chart, and third-party laboratory test reports for pesticides, heavy metals, and microbiological counts.

Yes. Our R&D team can tailor active marker percentages, pre-mix supercritical oleoresins with certified organic carrier oils (MCT, Sunflower Oil, Olive Oil), or produce spray-dried water-dispersible powder grades based on your specific formulation requirements.

Supercritical botanical oils and oleoresins should be kept in airtight, light-shielded containers (aluminum drums or dark glass) in a cool, dry environment between 15–25°C, away from direct heat and sunlight. Under recommended storage conditions, unopened containers carry a shelf life of 24 to 36 months.

Our standard MOQ is 1 kg for bulk supercritical oils and botanical oleoresins, and 100 g for high-purity monomer compounds. We provide complimentary 10–20 g evaluation samples with matching COA for qualified commercial formulators and laboratory testing prior to commercial order placement.

Request Specifications, Technical Files & Free Bulk Samples

Contact RAAG Biotech Co., Ltd. today with your desired active concentration, estimated annual volume, and destination country. Our technical specialists will respond within 24 hours with full specification sheets, current batch COA, and competitive factory pricing.

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