Direct factory supply featuring advanced Supercritical CO2 and solvent-free chromatography techniques. Every lot is batch-certified with full HPLC/UV assay documentation, zero pesticide residue panels, and complete regulatory traceability for Ghanaian importers.
Standardized raw botanical powder derived from Sophora Japonica. Designed for high-volume dietary supplement blending with ultra-low moisture and strict heavy metal control.
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Vibrant yellow botanical isolate processed under ISO-certified extraction controls. Excellent stability profile for pharmaceutical capsules, tablets, and topical formulations.
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Next-generation phospholipid encapsulation engineering yielding up to 20x cellular bio-availability compared to unformulated crystalline quercetin powder.
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Pharmaceutical-grade plant monomer refined through precision crystallization. Ideal for commercial beverage fortification and high-potency immune support products.
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Flexible form options (Anhydrous for water-sensitive capsules; Dihydrate for standard tableting). Packed in sealed fiber drums with moisture-barrier inner foil liners.
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Direct-from-source bulk botanical extract with fully transparent batch history. Rigorously screened for aflatoxins, micro-organisms, and heavy metals prior to export dispatch.
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Synergistic plant complex rich in organic silica and quercetin flavonoids. Extensively utilized in joint health formulations, bone density blends, and herbal teas.
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Non-dusting granular variant optimized for direct-compression tablet manufacturing. Reduces hopper bridging and improves flowability during automated high-speed compression.
Send an InquiryAs the global pharmaceutical and nutraceutical sectors demand cleaner, solvent-free plant actives, traditional solvent extraction methods relying on hexane, ethanol, or acetone face severe regulatory scrutiny and consumer backlash. For Ghanaian biopharmaceutical producers, traditional herbal medicine repackagers, and cosmeceutical developers, securing high-purity botanical extracts with zero chemical residue is no longer a luxury—it is a critical market differentiator.
Supercritical Fluid Extraction using carbon dioxide (SFE-CO2) stands at the pinnacle of modern green extraction engineering. By manipulating carbon dioxide beyond its critical temperature (31.1°C) and critical pressure (73.9 bar), the gas enters a supercritical fluid phase. In this unique thermodynamic state, CO2 exhibits the dense solvent power of a liquid combined with the low viscosity and high diffusivity of a gas. This allows the fluid to penetrate dense botanical cellular structures effortlessly and dissolve heat-sensitive bio-active lipophilic molecules, essential oils, phytosterols, and delicate polyphenols without causing thermal degradation.
| Technical Parameter | Supercritical CO2 Extraction (SFE) | Ethanol Reflux Extraction | Hexane Solvent Extraction | Hydro-Distillation / Steam |
|---|---|---|---|---|
| Operating Temperature | 32°C – 45°C (Ultra-Low Heat) | 60°C – 78°C (Moderate Heat) | 65°C – 70°C (Moderate Heat) | 100°C+ (Thermal Stress) |
| Solvent Residue in Extract | 0.0 ppm (100% Solvent-Free) | < 500 ppm (Requires Drying) | < 290 ppm (Toxic Residuals) | 0.0 ppm (Water Based Only) |
| Preservation of Active Monomers | > 98.5% Active Yield | 80% – 88% Retention | 75% – 82% Retention | < 65% (Destroys Volatiles) |
| Environmental & Safety Rating | GRAS / Non-Toxic / Recyclable | Flammable / VOC Emissions | Hazardous / Explosive Risk | Eco-Friendly / High Energy |
| Regulatory Acceptance (FDA / WHO / Ghana FDA) | Instant Approval / Clean Label | Requires Residual Solvent Test | Strict Limits / Red-Flagged | Standard Approval |
While pure CO2 is non-polar and excels at extracting non-polar lipids, essential oils, and carotenoids, RAAG Biotech integrates high-precision co-solvent dosing systems (such as food-grade ethanol modifiers at 1% to 10%). This expands the dielectric constant of the fluid, allowing us to selectively target moderately polar botanical molecules including pure Quercetin flavonoids, Sophora Japonica derivatives, and specialized polyphenols with surgical precision, leaving behind unwanted plant waxes, heavy chlorophyll, and inert tannins.
Ghana is rapidly transforming into West Africa's hub for bio-pharmaceutical research, herbal product manufacturing, and value-added agricultural processing. Direct access to standardized SFE-CO2 extracts and purified monomer intermediates unlocks vast commercial opportunities for local enterprises.
Ghana's Center for Plant Medicine Research (CPMR) and licensed herbal manufacturers require standardized raw ingredients to elevate traditional remedies into modern capsules and syrups. Blending pure Quercetin 98% or SFE botanical extracts ensures exact batch-to-batch chemical assay consistency, eliminating seasonal variance in finished products distributed across Greater Accra, Kumasi, and Tamale.
Ghana is world-renowned for its premium Cocoa butter and Shea butter production. By fortifying local shea butter bases with SFE-extracted lipophilic actives, Gromwell Root CO2 extracts, or Liposomal Quercetin 50%, Ghanaian skincare brands can export premium anti-aging creams, barrier-repair lotions, and UV-protective serums directly to European and North American luxury retail markets.
Consumer health awareness across West Africa has led to a surge in functional drinks, tonic shots, and wellness beverages. Water-soluble Quercetin formulations, granular quercetin, and botanical bio-silica (Wild Horsetail Extract) allow Ghanaian beverage bottlers to formulate shelf-stable, anti-inflammatory beverages without sediment fallout or harsh synthetic taste profiles.
Supporting Ghana’s "One District, One Factory" (1D1F) industrial development agenda, our direct factory supply provides local processing factories with standardized raw powders in 25kg bulk drums. We provide pilot-batch custom mesh grinding (80-200 mesh) and custom carrier selections (maltodextrin, organic starch) to seamlessly integrate into automated encapsulation lines.
High-purity monomers like Quercetin Dihydrate 98% meet USP/EP monograph requirements, allowing Ghanaian pharmaceutical manufacturers in Tema and Spintex industrial zones to formulate OTC tablets targeting allergies, cardiovascular health, and oxidative stress management with complete regulatory peace of mind.
The Food and Drugs Authority (FDA) of Ghana has intensified enforcement of L.I. 2258 and mandatory testing for imported botanical raw materials. Importers must supply batch-specific COAs detailing heavy metal limits (Lead < 3.0 ppm, Arsenic < 1.0 ppm, Mercury < 0.1 ppm) and pesticide panels. SFE-CO2 extracts natively satisfy these strict criteria because supercritical fluids do not carry heavy mineral contaminants during extraction.
With the African Continental Free Trade Area (AfCFTA) secretariat headquartered in Accra, Ghanaian phytopharmaceutical manufacturers are uniquely positioned to export finished wellness products across West Africa. Utilizing certified ISO/HALAL/KOSHER raw materials enables seamless cross-border tariff preference and regional compliance throughout the ECOWAS trading block.
Ghanaian agricultural processors are shifting away from shipping low-margin raw dried herbs. Local producers are seeking international SFE equipment suppliers and contract-extraction partners to process indigenous West African flora—such as Voacanga africana, Griffonia simplicifolia (5-HTP), and Hibiscus—into high-potency standardized powders for global markets.
Established in 2014, RAAG Biotech Co., Ltd. operates a GMP-audited production center equipped with multi-stage supercritical CO2 extractors, high-pressure column chromatography, and state-of-the-art spray drying systems. We bridge botanical nature and scientific precision.
Every shipment sent to Tema Port or Kotoka International Airport is tied to a contracted planting base lot code. Complete audit files include HPLC/UV assay reports, MSDS, technical data sheets, allergen statements, flow charts, and third-party SGS/Eurofins verification option.
Our manufacturing infrastructure is maintained under strict ISO22000, HACCP, HALAL, KOSHER, and Organic quality management systems. Our cleanrooms meet Class 100,000 pharmaceutical standards for micro-organism control.
Over 8 senior PhD R&D scientists assist Ghanaian clients with bespoke particle mesh size, custom bulk density, modified solubility profiles (water-dispersible oleoresins), and liposomal carrier customization before commercial scale-up.
We offer flexible shipping terms including FOB, CIF Tema Port, and DDP via express air freight for urgent R&D samples. Inner double-layer polyethylene bags inside heavy-duty aluminum foil pouches and drums protect powders against West Africa's humid tropical climate.
Direct technical clarity regarding customs clearance, FDA compliance, quality documentation, and logistics to West Africa.
Every shipment to Ghana is accompanied by a full export documentation dossier: batch-specific Certificate of Analysis (HPLC/UV assay), MSDS, Specification Sheet, Process Flow Chart, Heavy Metal & Pesticide Screening Report, Microbiological Test Certificate, and Certificate of Origin. We also supply GSP Form E or ISO/HALAL certificates required by Ghana Revenue Authority (GRA) Customs Division and Ghana FDA for expedited import clearance.
Supercritical CO2 extracts are 100% water-free and solvent-free oleoresins or purified powders. In Ghana's high ambient humidity and temperature, traditional ethanol extracts with residual water content can absorb moisture rapidly, leading to clumping, hydrolysis, or microbial growth. SFE-CO2 extracts possess far superior oxidative stability and extended shelf-life (24 to 36 months) without requiring heavy synthetic preservatives.
Our standard MOQ for commercial bulk standardized extracts and Quercetin powders is 1 kg (packed in sealed aluminum foil bags). For high-purity monomers or specialized liposomal grades, MOQ starts at 100 g. We offer free 10g–20g testing samples with a matching batch COA so your lab or third-party testing facility in Accra can verify purity, solubility, and mesh size prior to issuing a purchase order.
Yes. Our R&D application laboratory routinely customizes physical properties. We produce ultrafine micro-milled powders (up to 200 mesh) for fast capsule dissolution, granular non-dusting formats for direct tableting, and emulsified liquid nano-dispersions for transparent functional drinks and herbal teas.
In-stock products ship within 3 to 5 business days after order confirmation. Express air freight (DHL/FedEx/Air Cargo) to Kotoka International Airport (ACC) typically takes 5 to 8 days. Direct sea freight container shipments to Tema Port require approximately 28 to 35 transit days depending on vessel scheduling.
Yes. We collaborate with Ghanaian agricultural enterprises and research institutions under contract manufacturing agreements. Raw dried botanicals can be processed at our SFE-CO2 facility under NDA, converting local crops into high-value purified monomers or oleoresins returned to Ghana with certified HPLC purity metrics.
Request technical specifications, full batch COAs, zero-solvent compliance certificates, or request your free 20g verification sample delivered directly to your facility in Ghana.